2-MethoxyestradiolWhitecrystallinesolid.Anaturalmetaboliteof17b-estradiolwhichisdevoidofestrogenicactivity.Inhibitscellproliferationandangiogenesis.Markedlyinhibitstheneovascularizationofsolidtumorsandsuppressestumorgrowthinmice.Bindstothecolchicinebindingsiteoftubulin,andhasbeensuggestedtofunctionasanaturalregulatorofmicrotubulessemblyandfunction.Purity:≥90%byHPLC.CAS